scholarly journals A human testicular germ cell tumor with borderline histology between seminoma and embryonal carcinoma secreted beta-human chorionic gonadotropin and alpha-fetoprotein only as a xenograft

Cancer ◽  
1986 ◽  
Vol 58 (1) ◽  
pp. 139-146 ◽  
Author(s):  
Heinrich Walt ◽  
Stefan Arrenbrecht ◽  
C. Dawn Delozier-Blanchet ◽  
Paul J. Keller ◽  
Renate Nauer ◽  
...  
2008 ◽  
Vol 179 (3) ◽  
pp. 930-935 ◽  
Author(s):  
Akitoshi Takizawa ◽  
Takeshi Kishida ◽  
Takeshi Miura ◽  
Yusuke Hattori ◽  
Kazumi Noguchi ◽  
...  

Author(s):  
Pamela K. Cochran ◽  
Allen R. Chauvenet ◽  
P. Suzanne Hart ◽  
Siebold S.N. de Graaf ◽  
Barbara Cushing ◽  
...  

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Houda Alatassi ◽  
Brittany E. O’Bryan ◽  
Jamie C. Messer ◽  
Zhenglong Wang

Adult extrarenal nephroblastoma is a very rare tumor. Nephroblastoma arising from primary testicular germ cell tumor is exceedingly rare. To our knowledge, only three cases have been reported in the English literature. We report a case of a 19-year-old man who presented with a large right testicle. Image studies showed a large retroperitoneal mass along with liver and lung metastases. Orchiectomy demonstrated a mixed germ cell tumor composed of yolk sac tumor, embryonal carcinoma, and mature and immature teratoma with a significant portion of nephroblastoma. The patient received chemotherapy and no recurrence was noted during six months of followup. WT-1 expression was also studied due to the lack of consistency of its expression in testicular nephroblastoma in the literature. We also present a discussion and review of the literature due to its rarity, which indicate an adverse prognosis for patients with nephroblastoma components receiving standard chemotherapeutical regimes for testicular germ cell tumors.


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